{"id":6349,"date":"2025-10-15T23:47:18","date_gmt":"2025-10-15T20:47:18","guid":{"rendered":"https:\/\/theoutlet.sa\/?post_type=product&p=6349"},"modified":"2025-10-15T23:49:23","modified_gmt":"2025-10-15T20:49:23","slug":"calquence-100-mg-acalabrutinib-film-%e2%80%91-60-coated-tablets","status":"publish","type":"product","link":"https:\/\/theoutlet.sa\/ar\/\u0645\u0646\u062a\u062c\/calquence-100-mg-acalabrutinib-film-%e2%80%91-60-coated-tablets\/","title":{"rendered":"Calquence 100 mg acalabrutinib film \u2011 60 coated Tablets"},"content":{"rendered":"

Brand Name:<\/strong>\u00a0Calquence\u00ae<\/p>\n

Generic Name:<\/strong>\u00a0Acalabrutinib<\/p>\n

Form:<\/strong>\u00a0Film-coated tablets<\/p>\n

Strength:<\/strong>\u00a0100 mg<\/p>\n

Route:<\/strong>\u00a0Oral use<\/p>\n

Initial U.S. FDA Approval:<\/strong>\u00a02017<\/p>\n

Indications and Usage<\/strong><\/h4>\n

Mantle Cell Lymphoma (MCL):<\/strong><\/p>\n

For adults who have received at least one prior therapy.<\/p>\n

Approved under accelerated approval based on overall response rate.<\/p>\n

Continued approval may depend on confirmatory clinical trial outcomes.<\/p>\n

Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL):<\/strong><\/p>\n

Indicated for adult patients.<\/p>\n

Dosage and Administration<\/strong><\/p>\n

Recommended Dose:<\/strong>\u00a0100 mg orally every 12 hours.<\/p>\n

Administration:<\/strong>\u00a0Swallow whole with water, with or without food.<\/p>\n

Do Not:<\/strong>\u00a0Chew, crush, dissolve, or cut the tablets.<\/p>\n

Toxicity Management:<\/strong>\u00a0Use treatment interruption, dose reduction, or discontinuation.<\/p>\n

Hepatic Impairment:<\/strong>\u00a0Avoid use in severe hepatic impairment.<\/p>\n

Dosage Forms and Strengths<\/strong><\/p>\n

Tablet:<\/strong>\u00a0100 mg<\/p>\n

Contraindications<\/strong><\/p>\n

None<\/p>\n

Warnings and Precautions<\/strong><\/p>\n

Infections:<\/strong>\u00a0Risk of serious and opportunistic infections; monitor and treat promptly.<\/p>\n

Cytopenias:<\/strong>\u00a0Regular monitoring of blood counts is required.<\/p>\n

Second Primary Malignancies:<\/strong>\u00a0Includes skin cancers and solid tumors; advise sun protection.<\/p>\n

Atrial Fibrillation and Flutter:<\/strong>\u00a0Monitor for arrhythmia symptoms and manage accordingly.<\/p>\n

Adverse Reactions<\/strong><\/p>\n

Most common (\u226530%):<\/p>\n

Anemia<\/p>\n

Neutropenia<\/p>\n

Upper respiratory tract infection<\/p>\n

Thrombocytopenia<\/p>\n

Headache<\/p>\n

Diarrhea<\/p>\n

Musculoskeletal pain<\/p>\n

Drug Interactions<\/strong><\/p>\n

Strong CYP3A Inhibitors:<\/strong>\u00a0Avoid use.<\/p>\n

Moderate CYP3A Inhibitors:<\/strong>\u00a0Dose reduction required.<\/p>\n

Strong CYP3A Inducers:<\/strong>\u00a0Avoid or increase dose if unavoidable.<\/p>\n

Use in Specific Populations<\/strong><\/p>\n

Pregnancy:<\/strong>\u00a0May cause fetal harm and dystocia.<\/p>\n

Lactation:<\/strong>\u00a0Breastfeeding not recommended.<\/p>\n

Severe Hepatic Impairment:<\/strong>\u00a0Avoid use.<\/p>\n","protected":false},"excerpt":{"rendered":"

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  • Product Form: Tablets<\/li>\n
  • Quantity: 60 Tablets<\/li>\n<\/ul>\n","protected":false},"featured_media":6350,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[748],"product_cat":[692,749,420,424],"product_tag":[],"class_list":["post-6349","product","type-product","status-publish","has-post-thumbnail","product_brand-calquence","product_cat-cancer-treatments","product_cat-chronic-lymphocytic-leukemia","product_cat-pharmacy","product_cat-rx-treatments","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/product\/6349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/comments?post=6349"}],"version-history":[{"count":0,"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/product\/6349\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/media\/6350"}],"wp:attachment":[{"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/media?parent=6349"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/product_brand?post=6349"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/product_cat?post=6349"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/theoutlet.sa\/ar\/wp-json\/wp\/v2\/product_tag?post=6349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}