Imbruvica 140 mg Ibrutinib Tablets 30 Count

IMBRUVICA is a medicine against cancer, which contains the active substance ibrutinib.

• • It belongs to a group of drugs called protein kinase inhibitors.

What IMBRUVICA is used for:

It is used to treat the following types of blood cancer in adults:

• • Mantle cell lymphoma (MCL), a type of cancer that affects the lymph nodes, when the disease has returned or treatment has not worked.

• • Chronic lymphocytic leukemia(CLL), a type of cancer that affects white blood cells called lymphocytes, which also includes the lymph nodes.

• • IMBRUVICA is used in patients who have not been treated for CLL before or when the disease has returned or the treatment has not had an effect.

• • Waldenström’s macroglobulinemia(WM), a type of cancer that affects white blood cells called lymphocytes. It is used in patients who have not been treated forWMin the past or when the disease has come back or treatment has not worked, or in patients who cannot be given chemotherapy together with an antibody.

How to use:

• • Always use this medicine exactly as your doctor, pharmacist or nurse has told you.

• • Contact a doctor, pharmacist or nurse if you are unsure.

How much to take:

• • Mantle cell lymphoma (MCL)
    The recommended dose of IMBRUVICA is 560 mg once daily.

• • Chronic lymphocytic leukemia(CLL) /Waldenström’s macroglobulinemia(WM)

• • The recommended dose of IMBRUVICA is 420 mg once daily.

• • Your doctor may need to adjust your dose.

Taking this medicine:

• • Take the tablets orally (by mouth) with a glass of water.

• • Take the tablets at about the same time each day.

• • Swallow the tablets whole.Do not crush or chew them.

If you take too much IMBRUVICA:

• • Talk to a doctor or see a hospital immediately if you take too much IMBRUVICA.

• • Take the tablets and medicine leaflet with you.

If you forget to take IMBRUVICA:

• • If you have forgotten a dose, it can be taken as soon as possible on the same day, and the usual dosing schedule is continued the next day.

• • You should not take a double dose to replace a missed dose.

• • Ask your doctor, pharmacist or nurse if you are unsure when to take your next dose.

If you stop treatment with IMBRUVICA:

• • Do not stop treatment with this medicine unless your doctor tells you to do so.

• • Ask your doctor, pharmacist or nurse if you have any questions about the use of this medicine.

How IMBRUVICA works:

• • IMBRUVICA works by blocking “Bruton’s tyrosine kinase”, a protein in the body that helps cancer cells grow and survive in MCL, CLL and WM.

• By blocking this protein, IMBRUVICA helps to kill and reduce the number of cancer cells. It also slows down the development of cancer.