Aromasin 25 mg exemestane Tablets × 30

What Exemestane is and what it is used for:

• • Exemestane belongs to a group of medicines known as aromatase inhibitors.

• • Aromatase Inhibitors interfere with a substance called aromatase, which is needed to produce the female sex hormones, called oestrogens, especially in postmenopausal women.

• • Reduction in estrogen levels in the body is a way of treating hormone dependent breast cancer.

Exemestane is used:

• • To treat hormone dependent early breast cancer in postmenopausal women after they have completed 2-3 years of treatment with the medicine tamoxifen

• • To treat hormone dependent advanced breast cancer in postmenopausal women when a different hormonal drug treatment has not worked well enough.

What you need to know before you use Exemestane:

Do not use Exemestane:

Tell your doctor if you:

• • If you are allergic (hypersensitive) to exemestane or any of the other ingredients of this medicine

• • If you have not already been through ‘the menopause’, i.e. you are still having your monthly period,

• • If you are pregnant, or are likely to be pregnant

• • If you are breast-feeding.

Warnings and precautions:

You should let your doctor know:

• • If you have problems with your liver or kidneys.

• • If you have a history or are suffering from any condition which affects the strength of your bones(e.g. Osteoprosis).

Other medicines and Exemestane:

• • Exemestane should not be given at the same time as estrogen-containing medicines, for example hormone replacement therapy (HRT).

• • The following medicines should be used cautiously when taking Exemestane:

• • Rifampicin (an antibiotic),

• • Carbamazepine or phenytoin (medicines used to treat epilepsy),

• • The herbal remedy St Johns Wort (Hypericum perforatum), or preparations containing it.

How to use Exemestane:

• • Always take this medicine exactly as your doctor has told you.

• • Check with your doctor or pharmacist if you are not sure.

Dosage:

• • Adults and the elderly

• • The recommended dose is one tablet daily after a meal, at approximately the same time each day.

• • Use in children and adolescents

• • Exemestane is not suitable for children and adolescents under the age of 18.

Method of administration:

• • You should take Exemestane tablets by mouth.

• • Do not chew the tablets.

• • You can swallow the tablets with some liquid (e.g.a glass of water, 200ml).

• • Your doctor will tell you how long you should take Exemestane tablets.

Possible side effects:

• • Stop using the product and seek immediate medical attention if

• • You have signs of a decreased number of white blood cells called leucocytes.

• • Symptoms can include frequent infections, fatigue, sleepiness, fever and headache.

• • You have signs of a decreased number of blood cells called platelets.

• • Symptoms can include brusing easily, prolonged bleeding from cuts, bleeding gums, nose bleeds, fatigue and yellowing of the skin and/or whites of the eyes (jaundice).

• • Your bones seem weaker and/or have been easily fracturered as this may indicate that your bones have thinned and weakend (osteoporosis).

How to store Exemestane:

• • Store below 30°C in a dry place.

• • Store in the original container in order to protect from light.

• Keep out of the sight and reach of children.